MXD3 Antibody, HRP conjugated

Datasheet

Code	CSB-PA015252LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MXD3 Polyclonal antibody

Uniprot No.

Q9BW11

Target Names

MXD3

Alternative Names

bHLHc13 antibody; Class C basic helix-loop-helix protein 13 antibody; FLJ35523 antibody; Likely ortholog of mouse Max dimerization protein 3 antibody; MAD3_HUMAN antibody; MAX dimerization protein 3 antibody; Max dimerizer 3 antibody; Max-associated protein 3 antibody; Max-interacting transcriptional repressor MAD3 antibody; MGC2383 antibody; mxd3 antibody; Myx antibody; OTTHUMP00000223596 antibody; OTTHUMP00000223598 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Max dimerization protein 3 protein (1-206AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.

Gene References into Functions

results indicate that MXD3 is a potential new target and that the use of MXD3 siRNA nanocomplexes is a novel therapeutic approach for neuroblastoma PMID: 28419087
The results suggest that MXD3 is important for survival of Reh preB ALL cells, possibly as an anti-apoptotic factor. PMID: 25554682
Acute MXD3 activation results in a transient increase in DAOY cell proliferation while persistent activation of MXD3 results in an overall decrease in cell number, suggesting that the time course of MXD3 expression dictates the cellular outcome. PMID: 25053245
Increased level and/or duration of MXD3 expression ultimately reduces cell numbers via increased cell death and cell cycle arrest in medulloblastoma cells. PMID: 22808009

Subcellular Location

Nucleus.

Database Links

HGNC: 14008

OMIM: 609450

KEGG: hsa:83463

STRING: 9606.ENSP00000401867

UniGene: Hs.743332

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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